Zero Trust security for AI agents

Apply Zero Trust controls to every AI agent in your environment across identity, tool usage, and data access. Extend Conditional Access in Microsoft Entra to evaluate every agent authorization request in real time against the same risk signals as human users. Assign each agent its own managed identity with Entra Agent ID and scope permissions with Access Packages. Govern your MCP catalog as a software supply chain — unapproved tools don't run, and approved servers lock behind Azure API Management.

Log every agent tool call, API access, and data lookup into Microsoft Sentinel for continuous anomaly detection. Purview Insider Risk Management auto-assigns risk levels so you can investigate fast or revoke access entirely. DLP and sensitivity labels in Microsoft Purview restrict what agents can reach and auto-inherit to everything they generate, and Data Access Governance maps exactly what each agent can access before a prompt fires. 

Jeremy Chapman, Microsoft 365 Director, shares how to put these controls into practice across every managed, self-hosted, and shadow agent in your estate.

► QUICK LINKS:

00:00 - How AI changes Zero Trust

01:20 - Zero Trust principles

02:27 - How to apply Zero Trust principles

03:40 - Conditional Access for Agent Identities

04:59 - Entra Agent ID + Access Packages

06:07 - Runtime Observability

06:58 - DLP, Sensitivity Labels + Data Access Governance

07:47 - MCP catalog

08:36 - AI apps & experiences

09:24 - Wrap up

► Link References 

Watch the rest of this series at https://aka.ms/ZTMechanics

For additional resources, check out https://aka.ms/GoZeroTrust

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